Sudden death due to undetected mediastinal germ cell tumor.
Sudden death due to undetected mediastinal germ cell tumor. Sanchez- Hermosillo E, Sikirica M, Carter D, Valigorsky JM. Department of Pathology and .
http://www.ncbi.nlm.nih.gov/pubmed/9539396
Super-high-risk germ-cell tumors: a clinical entity. Report of eleven ...
Among patients suffering from nonseminomatous germ-cell tumor, with a poor prognosis, a subset underwent respiratory failure and died very early in the course .
http://www.ncbi.nlm.nih.gov/pubmed/8087445Testicular Cancer Home Page - National Cancer Institute
Most testicular cancers begin in germ cells (cells that make sperm) and are called testicular germ cell tumors. Estimated new cases and deaths from testicular .
http://www.cancer.gov/cancertopics/types/testicularOvarian Cancer Home Page - National Cancer Institute
Report to Nation Finds Continuing Declines in Cancer Death Rates . begins in the cells on the surface of the ovary) or malignant germ cell tumors (cancer that .
http://www.cancer.gov/cancertopics/types/ovarianGerm Cell Tumors - eMedicine - Medscape
Apr 2, 2012. against apoptotic death because of the oncogenic effect of CCND2, . Increased risk of testicular germ cell cancer among infertile men.
http://emedicine.medscape.com/article/279007-overviewCell Death and Differentiation - Loss of drug-induced activation of ...
Testicular germ cell tumors (TGCTs) are unusually sensitive to cisplatin. In the present study the role of the CD95 death pathway in cisplatin sensitivity of TGCT .
http://www.nature.com/cdd/journal/v10/n7/full/4401248a.htmlInitial chemotherapy for advanced testicular germ cell tumors
Mar 13, 2012 . Testicular cancers, 95 percent of which are germ cell tumors (GCTS), . accounted for about 10 percent of all cancer deaths in men between the .
http://www.uptodate.com/contents/initial-chemotherapy-for-advanced-testicular-germ-cell-tumorsPrimary Mediastinal Nonseminomatous Germ Cell Tumors: Results ...
germ cell tumors (NSGCT) are uncommon neoplasms . All patients who did not achieve a CR died of . developed and subsequently died of a hematologic .
http://jco.ascopubs.org/content/16/2/725.full.pdf
Management of Primary Malignant Germ Cell Tumor of the ...
Background: Primary mediastinal malignant germ cell tumors (GCTs) are rare . Operative death was defined as any death within 30 days of the operation or .
http://jjco.oxfordjournals.org/content/34/7/386.fullCancer death at 24 leads to Wivenhoe family charity (From Essex ...
Apr 26, 2012 . Robin Freeman, of Queens Road, Wivenhoe, died in St Helena Hospice, Colchester, on December 10. He had a form of germ cell cancer that .
http://www.essexcountystandard.co.uk/news/9674041.Cancer_death_at_24_leads_to_Wivenhoe_family_charity/Recurrence of germ cell tumor after orchiectomy - Elsevier
One of 10 patients died of recurrent Stage I nonseminoma germ cell tumor. The chance of dying of recurrence after metastatic nonseminoma germ cell tumor .
http://linkinghub.elsevier.com/retrieve/pii/S0090429500006932Distinct p53-independent apoptotic cell death signalling pathways in ...
Nov 8, 1999 . Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines. Herman Burger1,; Kees Nooter1,*, .
http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-0215(19990517)81:4%3C620::AID-IJC19%3E3.0.CO;2-S/fullHigh-Dose Chemotherapy in Adult Patients With Germ Cell Tumors
Background: Approximately 80% of patients with advanced germ cell tumors ( GCTs) can be cured . arm did not receive HDC because of early death or tox- .
http://www.moffitt.org/CCJRoot/v10n1/pdf/48.pdfHijacking Germ Cells for Cancer: Examining a 'Dead End' in Male ...
Hijacking Germ Cells for Cancer: Examining a 'Dead End' in Male Germ Cell Development. Cook, Matthew Simon. URI: http://hdl.handle.net/10161/2414 .
http://dukespace.lib.duke.edu/dspace/handle/10161/2414Anterior mediastinal nonseminomatous germ cell tumor with malignant
Dec 8, 2004 . Furthermore, multivariate analysis suggested 3 independent predictors of death: ( 1) persistent germ cell tumor in the residual mass, .
http://www.sciencedirect.com/science/article/pii/S0149794404000923Extragonadal Germ Cell Cancer
Jan 17, 2007 . The Testicular Cancer Resource Center - Extragonadal Germ Cell Cancer. . tumor where the primary tumor has "burnt out" or died on its own.
http://tcrc.acor.org/egc.htmlChemotherapy of Refractory Germ Cell Cancer with Etoposide
alopecia, and myelosuppression. There were no treat- ment-related deaths. Five (42%) of 12 patients with primary gonadal germ-cell cancer achieved a com- .
http://jco.ascopubs.org/content/1/11/706.full.pdfProgrammed cell death in response to chemotherapeutic agents in ...
Programmed cell death in response to chemotherapeutic agents in human germ cell tumour lines. Huddart RA, Titley J, Robertson D, Williams GT, Horwich A, .
http://www.ncbi.nlm.nih.gov/pubmed/7640048Cancer patients fight lonely battle
Feb 13, 2012 . 12: Down with grade I germ cell cancer, 30-year-old Yuvraj Singh has . the grassroots to treat cancer patients, the disease means virtual death .
http://www.telegraphindia.com/1120213/jsp/bihar/story_15114045.jspCURING METASTATIC CANCER: LESSONS FROM TESTICULAR ...
DNA, leading to cell death. But what is . In 1970, 95% of men with metastatic TGCTs died of . a germ-cell tumour, it is believed that the cells pass through a .
http://www.stanford.edu/class/cbio101/coursework/masters2003.pdfCell Death and Disease - Disruption of the MDM2-p53 interaction ...
Apr 21, 2011 . Citation: Cell Death and Disease (2011) 2, e148; doi:10.1038/cddis.2011.33 . Horwich A, Shipley J, Huddart R. Testicular germ-cell cancer.
http://www.nature.com/cddis/journal/v2/n4/full/cddis201133a.htmlExtragonadal germ cell tumors
with the loss of the long arm of chromosome 12 is seen in nearly all germ cell cancers of primary gonadal and extra- gonadal origin [5, 6]. This concept, however .
http://www.hem-aids.ru/system/files/attachments/687/mediastinal_germ_cell_tumors_mediastinal_germ_cell_pdf_004.pdfHigh-Dose Chemotherapy for Germ Cell Tumors: The European ...
High-dose chemotherapy for germ cell tumors is alive and well in Europe, with more than 300 patients treated each year. The mortality rate in 1999 was 3%, and .
http://mmserver.cjp.com/gems/blood/ABMT.10.Rosti1.pdfWHERE “CANCER” DOES NOT SPELL “DEATH”: THE ...
“DEATH”: THE TESTICULAR GERM. CELL. Mihai Marinca*, Lucian Miron**. Andreea Marinca***, Ingrith Miron****. Abstract. Testicular cancer accounts for only .
http://eng.bioetica.ro/atdoc/RRBv8n3_2010_Marinca_EN.pdfMalignant Mixed Germ Cell Tumour of the Ovary in a 10-year-old Girl
Feb 4, 2007 . mixed germ cell tumour who died 2 months after ini- tial symptom presentation to illustrate the aggressive behaviour of this tumour and the .
http://www.hkcr.org/publ/Journal/counter.php?ref=vol11no2/full/092-095%20Malignant.pdfSudden death caused by testicular germ cell tumour
Sudden death caused by testicular germ cell tumour. Dada M.A. Van Velden D.J.J.. URI: http://hdl.handle.net/10019.1/14186. Date: 1995 .
http://scholar.sun.ac.za/handle/10019.1/14186Transcripts that associate with the RNA binding protein, DEAD-END ...
Aug 18, 2011 . testicular germ cell tumors [5-7]. Thus, on the 129 back- ground, some germ cells escape death to undergo cancer- ous transformation.
http://www.biomedcentral.com/content/pdf/1471-2199-12-37.pdfManagement of Recurrent Testicular Germ Cell Tumors
Approximately 8000 new cases and 400 deaths from testicular cancer are expected in the United States in 2006 [1]. In men 15–35 years old, testicular germ cell .
http://theoncologist.alphamedpress.org/content/12/1/51.fullMolecular Determinants of Treatment Response in Human Germ Cell
Purpose: Germ cell tumors (GCTs) are highly sensitive to cisplatin-based . damage has to be detected to activate an apoptotic cascade leading to cell death .
http://clincancerres.aacrjournals.org/content/9/2/767.fullPerinatal Programming of Adult Rat Germ Cell Death After Exposure ...
Feb 14, 2012 . disruptors can induce long-term testicular germ cell death probably through . tension, type 2 diabetes, and cancer, which have become .
http://endo.endojournals.org/content/early/2012/02/08/en.2011-1109.full.pdfPerinatal Programming of Adult Rat Germ Cell Death After Exposure ...
Feb 14, 2012 . disruptors can induce long-term testicular germ cell death probably through . tension, type 2 diabetes, and cancer, which have become .
http://endo.endojournals.org/content/early/2012/02/08/en.2011-1109.full.pdfMale germ cell apoptosis: regulation and biology
May 27, 2010 . 1Cell Death and Differentiation Research Laboratory, National Institute . Since instances of germ cell carcinoma have increased over the past .
http://rstb.royalsocietypublishing.org/content/365/1546/1501.fullSurgical salvage therapy for malignant intrathoracic metastases from ...
metastatic nonseminomatous germ cell cancer of testicular origin. . increasing incidence of testicular NSGCTs, mortality rates have dramatically de- creased .
http://surgery.uc.edu/content/Education/residentresources/Thoracic/Kesler_Surgical%20salvage%20therapy%20-%20JTCVS.pdfOvarian Cancer | Cancer.Net
Feb 9, 2012 . The ovaries are the glands containing the germ cells or eggs. . cancer and fifth most common cause of cancer-related death in women.
http://www.cancer.net/patient/Cancer+Types/Ovarian+Cancer/ci.Ovarian+Cancer.printerSmoking cessation in long-term survivors of germ cell tumour
central nervous system relapse of germ cell tumor. (n = 1). The causes of death are unknown in two patients. Discussion. The major finding from our cohort study .
http://palliativmedizin.klinikum.uni-muenchen.de/docs/8199.pdfMalignant Germ Cell Tumors of the Ovary : Obstetrics & Gynecology
When considered together, the dysgerminoma, yolk sac tumor, immature teratoma, and their hybrid-the mixed germ cell tumor-comprise more than 90% of .
http://journals.lww.com/greenjournal/Fulltext/2000/01000/Malignant_Germ_Cell_Tumors_of_the_Ovary.24.aspxUniversity of Texas - College of Pharmacy - Pharmacology ...
Germ cell tumors are the most common types of testicular cancer in men 15 to 34 . may more efficiently exploit the sensitivity of germ cells to death by apoptosis .
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/richburg.htmlSteel factor controls midline cell death of primordial germ cells and ...
in midline structures at this stage. Midline germ cell death is important. Extragonadal germ cell tumors are common human pediatric tumors, and almost always .
http://dev.biologists.org/content/133/24/4861.full.pdfThe Role of dead?end in Germ?cell Tumor Development
strain, inactivation of the dead-end (Dnd1) gene, and the ongoing studies on Dnd1 to understand its role in germ-cell and germ cell-tumor devel- opment, are .
http://onlinelibrary.wiley.com/doi/10.1196/annals.1411.006/pdfLong-Term Outcome of Patients with Relapsed and Refractory Germ ...
Of the 12 complete responders, 5 relapsed, and 1 died of treatment-related acute leukemia 27.5 months after treatment without evidence of germ cell cancer. Six .
http://www.annals.org/content/117/2/124.full.pdfMalignant Germ Cell Sacrococcygeal Tumors in Children Improved ...
Non-seminomatous malignant germ cell tumors are un- common malignancies . Died. Progressive disease. Died 1 m. Lung metastases. Local + CNS relapse .
http://informahealthcare.com/doi/abs/10.3109/02841868909111257malignant tumor - definition of malignant tumor in the Medical ...
germ cell tumor any of a group of tumors arising from primitive germ cells, usually of the . A malignant tumor may cause death if treatment does not intervene.
http://medical-dictionary.thefreedictionary.com/malignant+tumorBrain as sanctuary site of relapse in germ cell cancer patients ...
Mar 2, 2012 . Results: Of 1049 patients treated for metastatic germ cell cancer, 15 were . for limited systemic relapse and the sixth has relapsed and died.
http://eprints.soton.ac.uk/26257/A molecular evaluation of germ cell death induced by etoposide in ...
Apr 4, 2009 . The mechanism underlying apoptosis induction in cancer cells has . To confirm that germ cell death was driven by caspase activation, we .
http://molehr.oxfordjournals.org/content/15/6/363.fullHow are extragonadal germ cell tumors diagnosed? - Sharecare
. procedures, blood tests, and tissue sample analyses to diagnose a germ cell tumor. . Nonseminomas are more likely to spread rapidly and cause death.
http://www.sharecare.com/question/extragonadal-germ-cell-tumors-diagnosedLate relapse of metastatic testicular nonseminomatous germ cell ...
Five (25%) patients were initially treated with chemotherapy for late relapse; three of them died from progressive germ cell cancer and the two survivors both had .
http://www.urologiconcology.org/article/S1078-1439(07)00018-X/abstractLong-Term Follow-Up of a Phase III Study of Three Versus Four ...
nated germ-cell tumors were randomized to either three or four courses . Survival was defined from date onto study until date of death or date last known alive .
http://jco.ascopubs.org/content/16/2/702.full.pdfTreatment of testicular germ-cell cancer: a cochrane evidence ...
Testicular germ-cell cancer is relatively rare, affecting less than 6 men per 100000 in the UK, . There were 10 deaths in patients receiving BEP (3%) compared .
http://medres.med.ucla.edu/Education/syllabus/solid/pdf/29%20Testicular%20Cancer.pdfScreening for long-term germ cell cancer survivors
MKSAP: 45-year-old man with a mediastinal germ cell tumor . Screening recommendations for survivors of germ cell cancer are no different than those for the .
http://www.kevinmd.com/blog/2012/03/mksap-45yearold-man-mediastinal-germ-cell-tumor.htmlJust months after my snooker star husband felt pains in his side he ...
Aug 28, 2007 . Within months, the man I adored was dead' . A subsequent scan ruled out a germ cell cancer, and the consultant broke the bad news that .
http://www.dailymail.co.uk/health/article-478155/Just-months-snooker-star-husband-felt-pains-dead.htmlIntensive chemotherapy and radical resections for primary ...
Primary nonseminomatous germ cell tumors of the mediastinum (PNSGM), unlike malignancies of gonadal origin, . There were 3 chemotherapy related deaths.
http://ats.ctsnetjournals.org/cgi/content/full/69/2/337BAX-mediated cell death affects early germ cell loss and incidence ...
Testicular germ cell tumor. A homozygous nonsense mutation (Ter) in murine Dnd1 (Dnd1Ter/Ter) results in a significant early loss of primordial germ cells .
http://www.cellbio.duke.edu/faculty/capel/Cook_Bax_2009.pdfHigh-Dose Chemotherapy and Stem-Cell Rescue for Metastatic ...
Jul 26, 2007 . Germ-cell tumors are curable even in the presence of metastatic . from the initiation of high-dose chemotherapy to tumor progression or death.
http://www.nejm.org/doi/full/10.1056/NEJMoa067749
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